Journal: The British Journal of Nutrition
Article Title: Effects of diets containing fish oils or fish oil concentrates with high cetoleic acid content on the circulating cholesterol concentration in rodents. A systematic review and meta-analysis
doi: 10.1017/S0007114523002118
Figure Lengend Snippet: Subgroup analyses for meta-analysis using a random effects model presenting the effects of intake of CA-rich fish oils and concentrates on circulating total cholesterol concentration (mmol/l) as a forest plot; experiments using intervention diets containing fish oil v . diets containing LC-MUFA or CA concentrates (a), experiments using comparison diets containing vegetable fat (corn oil, olive oil, or soybean oil) v diets containing animal fat (lard or milk fat) (b). CI; confidence interval. The studies are described as intervention diet (type of fish oil or concentrate), comparator diet (type of fat), rodent strain, sex of the rodents, first author and year of publication. Abbreviations used: Type of fish or concentrate: LCMUFA-conc; long-chain monounsaturated fatty acid concentrate, CA-conc; cetoleic acid concentrate. Rodent strain: apoE; apolipoprotein E null mice, C57; C57BL/6J mice, KKAy; KK-A y mice, LDLRKO; LDL receptor knockout mice, LE; W; Wistar rats, Z; Zucker fa/fa rats. Sex of the rodents: F; female, M; male.
Article Snippet: Based on the stated bodyweights for the Wistar rats where age were not declared, we used the Charles River growth chart for male Wistar rats ( ) to estimate the age at baseline to be approximately 5–7 weeks for male Wistar rats weighing 175–185 g ( ) , 5–8 weeks for male Wistar rats weighing 195–225 g ( ) and 4–6 weeks for male Wistar rats weighing 120 g ( ) .
Techniques: Concentration Assay, Comparison, Knock-Out